⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5579375 | 0.81 | — | — | |
| SCHEMBL2297041 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL4766167 | 0.70 | — | — | |
| SCHEMBL17966730 | 0.66 | — | — | |
| SCHEMBL17476751 | 0.65 | — | — | |
| SCHEMBL2231541 | 0.61 | — | — | |
| SCHEMBL28302994 | 0.57 | — | — | |
| SCHEMBL29092306 | 0.56 | GABRR1 (0.33) | — | |
| SCHEMBL18978537 | 0.54 | GABRR1 (0.34) | — | |
| SCHEMBL23189253 | 0.53 | PLA2G2A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613634-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004087714-A1 | INDOLE ACETAMIDES AS INHIBITORS OF THE HEPATITIS C VIRUS NS5B POLYMERASE | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2004-10-14 | — | — | WO | disclosed |