Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.59 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756401 | 1.00 | CCR2 (0.59) | CCR2MAOAMAOBCTSK | |
| SCHEMBL2991013 | 1.00 | CCR2 (0.59) | CCR2MAOAMAOBCTSK | |
| SCHEMBL2989275 | 0.92 | CCR2 (0.67) | CCR2 | |
| SCHEMBL5757649 | 0.92 | CCR2 (0.67) | CCR2 | |
| SCHEMBL3425636 | 0.92 | CCR2 (0.67) | CCR2 | |
| SCHEMBL2990164 | 0.87 | CCR2 (0.57) | CCR2MAOAMAOBCTSK | |
| SCHEMBL3424689 | 0.87 | CCR2 (0.57) | CCR2MAOAMAOBCTSK | |
| SCHEMBL5757482 | 0.87 | CCR2 (0.57) | CCR2MAOAMAOBCTSK | |
| SCHEMBL2986117 | 0.84 | CCR2 (0.62) | CCR2MAOAMAOBCTSK | |
| SCHEMBL3427293 | 0.83 | CCR2 (0.60) | CCR2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1483241-A4 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL MYERS SQUIBB CO (US) | 2006-12-13 | — | — | EP | disclosed |
| EP-1483241-A2 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Company (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003075853-A2 | CYCLIC DERIVATIVES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-09-18 | — | — | WO | disclosed |