Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | REN | P00797 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | GLP1R | P43220 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757009 | 0.85 | CACNA1B (0.57) | CACNA1BGSK3AGSK3BATMHSD17B10 | |
| SCHEMBL5756038 | 0.85 | CACNA1B (0.46) | CACNA1BATMHSD17B10KMT2AMEN1 | |
| SCHEMBL4841915 | 0.83 | CACNA1B (0.59) | CACNA1BATMHSD17B10MCL1KMT2A | |
| SCHEMBL5348579 | 0.81 | CACNA1B (0.52) | CACNA1BATMHSD17B10MCL1KMT2A | |
| SCHEMBL5118885 | 0.78 | ATM (0.44) | CACNA1BATMHSD17B10MCL1KMT2A | |
| SCHEMBL5110973 | 0.78 | CACNA1B (0.46) | CACNA1BATMHSD17B10MCL1REN | |
| SCHEMBL5361323 | 0.77 | CACNA1B (0.61) | CACNA1BMAPK14 | |
| SCHEMBL5123633 | 0.77 | CACNA1B (0.43) | CACNA1BATMHSD17B10MCL1KMT2A | |
| Hydrochloric Acid SCHEMBL5125659 | 0.77 | CACNA1B (0.46) | CACNA1BATMHSD17B10MCL1REN | |
| Bromide SCHEMBL5113742 | 0.77 | CACNA1B (0.46) | CACNA1BATMHSD17B10MCL1REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |