Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GALR3 | O60755 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | GRN | P28799 | 2/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5348579 | 0.90 | CACNA1B (0.52) | CACNA1BKMT2AGAAMEN1HSD17B10 | |
| SCHEMBL5754777 | 0.85 | CACNA1B (0.59) | CACNA1BKMT2AGAAMEN1RAB9A | |
| SCHEMBL5757014 | 0.85 | CACNA1B (0.44) | CACNA1BKMT2AMEN1HSD17B10ATM | |
| SCHEMBL5353066 | 0.84 | KMT2A (0.44) | CACNA1BKMT2AGAAMEN1RAB9A | |
| SCHEMBL4841915 | 0.83 | CACNA1B (0.59) | CACNA1BKMT2AMEN1HSD17B10ATM | |
| SCHEMBL5755765 | 0.80 | KMT2A (0.42) | KMT2AGAAMEN1RAB9ANPC1 | |
| SCHEMBL5348575 | 0.80 | CACNA1B (0.69) | CACNA1BKMT2AMEN1HSD17B10ATM | |
| SCHEMBL5117026 | 0.79 | ENPP2 (0.40) | CACNA1BKMT2AATM | |
| SCHEMBL5116993 | 0.79 | CACNA1B (0.41) | CACNA1BKMT2AMEN1HSD17B10ATM | |
| SCHEMBL5361820 | 0.79 | CACNA1B (0.51) | CACNA1BHSD17B10ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |
| EP-0997147-A1 | AMINO ACID DERIVATIVES | Ono Pharmaceutical Co., Ltd. (JP) | 2000-05-03 | — | — | EP | claimed |
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | disclosed |
| EP-0997147-A1 | AMINO ACID DERIVATIVES | Ono Pharmaceutical Co., Ltd. (JP) | 2000-05-03 | — | — | EP | disclosed |