Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 7/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.33 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.32 |
| ▸ | CTSS | P25774 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758645 | 0.95 | CACNA1B (0.43) | CACNA1BALDH1A1PSMB8P2RX7KMT2A | |
| SCHEMBL5754912 | 0.95 | CACNA1B (0.43) | CACNA1BALDH1A1PSMB8P2RX7KMT2A | |
| SCHEMBL5754438 | 0.95 | CACNA1B (0.51) | CACNA1BALDH1A1PSMB8HSD17B10CTSS | |
| SCHEMBL5757099 | 0.94 | CACNA1B (0.54) | CACNA1BALDH1A1PSMB8P2RX7KMT2A | |
| SCHEMBL5759035 | 0.89 | CACNA1B (0.49) | CACNA1BKMT2AHSD17B10 | |
| SCHEMBL5755981 | 0.88 | KMT2A (0.38) | CACNA1BALDH1A1P2RX7KMT2AHSD17B10 | |
| SCHEMBL5757463 | 0.88 | CACNA1B (0.61) | CACNA1BALDH1A1HSD17B10CTSS | |
| SCHEMBL5758199 | 0.87 | CACNA1B (0.43) | CACNA1BPSMB8PSMB9PSMB10HSD17B10 | |
| SCHEMBL5754736 | 0.86 | CACNA1B (0.40) | CACNA1BKMT2AHSD17B10 | |
| SCHEMBL5752573 | 0.86 | KDM4E (0.41) | CACNA1BALDH1A1PSMB8P2RX7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |