Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 1/20 | 0.43 |
| ▸ | YAP1 | P46937 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.39 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.36 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.36 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.36 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | GHSR | Q92847 | 3/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759035 | 0.93 | CACNA1B (0.49) | CACNA1BYAP1MCL1ACEHSD17B10 | |
| SCHEMBL5754912 | 0.93 | CACNA1B (0.43) | CACNA1BYAP1HSD17B10ATMPSMB8 | |
| SCHEMBL5758645 | 0.93 | CACNA1B (0.43) | CACNA1BYAP1HSD17B10ATMPSMB8 | |
| SCHEMBL5756778 | 0.91 | CACNA1B (0.38) | CACNA1BYAP1HSD17B10ATMGHSR | |
| SCHEMBL5754736 | 0.90 | CACNA1B (0.40) | CACNA1BHSD17B10ATM | |
| SCHEMBL5756658 | 0.88 | CACNA1B (0.39) | CACNA1BMCL1HSD17B10ATMBCL2 | |
| SCHEMBL5754438 | 0.87 | CACNA1B (0.51) | CACNA1BHSD17B10ATMPTPN1PSMB8 | |
| SCHEMBL5757036 | 0.87 | CACNA1B (0.45) | CACNA1BHSD17B10PSMB8PSMB9PSMB5 | |
| SCHEMBL5754795 | 0.87 | CACNA1B (0.43) | CACNA1BYAP1MCL1ACEHSD17B10 | |
| SCHEMBL5755981 | 0.86 | KMT2A (0.38) | CACNA1BYAP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |