Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | FOS | P01100 | 2/20 | 0.44 |
| ▸ | JUN | P05412 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761134 | 0.82 | NPC1 (0.58) | MAOBKDM4EALDH1A1MAPTPDGFRB | |
| SCHEMBL5757744 | 0.82 | MGAM (0.54) | HDAC2KDM4EMAPTPDGFRBPDGFRA | |
| SCHEMBL10465995 | 0.79 | MAOB (0.65) | MAOBKDM4EALDH1A1MAPTPDGFRB | |
| SCHEMBL8001650 | 0.78 | MAOB (0.71) | MAOBKDM4EALDH1A1MAPTPDGFRB | |
| SCHEMBL2003093 | 0.77 | MAPT (0.55) | HDAC2KDM4EALDH1A1MAPTTSHR | |
| SCHEMBL2202317 | 0.76 | MAOB (0.66) | MAOBPDGFRBPDGFRAKMT2ANPC1 | |
| SCHEMBL430324 | 0.76 | MGAM (0.59) | MAOBKDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL1285592 | 0.76 | MAOB (0.76) | MAOBKDM4EALDH1A1MAPTPDGFRB | |
| SCHEMBL264108 | 0.76 | MAOB (0.62) | MAOBALDH1A1MAPTPDGFRBPDGFRA | |
| SCHEMBL5647010 | 0.75 | MAOB (0.61) | MAOBALDH1A1MAPTPDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |
| EP-0912562-A1 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1999-05-06 | — | — | EP | disclosed |
| WO-1998003505-A2 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-01-29 | — | — | WO | disclosed |