Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 2/20 | 0.56 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.43 |
| ▸ | ATP4A | P20648 | 6/20 | 0.39 |
| ▸ | ATP4B | P51164 | 6/20 | 0.39 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.37 |
| ▸ | PPARA | Q07869 | 4/20 | 0.37 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.36 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5757081 | 1.00 | ERBB2 (0.56) | ERBB2MINK1FFAR1ATP4AATP4B | |
| SCHEMBL5755643 | 0.90 | ERBB2 (0.54) | ERBB2MINK1ATP4AATP4BHMOX1 | |
| SCHEMBL5755640 | 0.90 | ERBB2 (0.54) | ERBB2MINK1ATP4AATP4BHMOX1 | |
| SCHEMBL5790298 | 0.88 | ERBB2 (0.60) | ERBB2MINK1FFAR1ATP4AATP4B | |
| SCHEMBL5790299 | 0.88 | ERBB2 (0.60) | ERBB2MINK1FFAR1ATP4AATP4B | |
| SCHEMBL5759021 | 0.88 | ERBB2 (0.55) | ERBB2MINK1FFAR1ATP4AATP4B | |
| SCHEMBL5759019 | 0.88 | ERBB2 (0.55) | ERBB2MINK1FFAR1ATP4AATP4B | |
| SCHEMBL5760882 | 0.88 | ERBB2 (0.57) | ERBB2MINK1ATP4AATP4BHMOX1 | |
| SCHEMBL5760885 | 0.88 | ERBB2 (0.57) | ERBB2MINK1ATP4AATP4BHMOX1 | |
| SCHEMBL5761163 | 0.87 | ERBB2 (0.57) | ERBB2MINK1ATP4AATP4BHMOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |