Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERBB2 | P04626 | 2/20 | 0.60 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.60 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATP4A | P20648 | 5/20 | 0.35 |
| ▸ | ATP4B | P51164 | 5/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5790298 | 1.00 | ERBB2 (0.60) | ERBB2MINK1FFAR1TP53MAPT | |
| SCHEMBL26316546 | 0.89 | ERBB2 (0.63) | ERBB2MINK1FFAR1MAPTNPC1 | |
| SCHEMBL5759321 | 0.89 | ERBB2 (0.75) | ERBB2MINK1FFAR1MAPTHMOX1 | |
| SCHEMBL5759315 | 0.89 | ERBB2 (0.75) | ERBB2MINK1FFAR1MAPTHMOX1 | |
| SCHEMBL5759019 | 0.88 | ERBB2 (0.55) | ERBB2MINK1FFAR1HTTKMT2A | |
| SCHEMBL5759021 | 0.88 | ERBB2 (0.55) | ERBB2MINK1FFAR1HTTKMT2A | |
| SCHEMBL5757081 | 0.88 | ERBB2 (0.56) | ERBB2MINK1FFAR1HMOX1HTT | |
| SCHEMBL5757077 | 0.88 | ERBB2 (0.56) | ERBB2MINK1FFAR1HMOX1HTT | |
| SCHEMBL780445 | 0.88 | ERBB2 (0.55) | ERBB2MINK1FFAR1TP53MAPT | |
| SCHEMBL780446 | 0.88 | ERBB2 (0.55) | ERBB2MINK1FFAR1TP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |