Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5756938 | 0.94 | HTR2A (0.52) | KMT2ATDP1HTR2ACYP2D6KDM4E | |
| SCHEMBL5757056 | 0.83 | KCNH2 (0.56) | HTR2AKCNH2CYP2D6KDM4ECYP1A2 | |
| SCHEMBL5754009 | 0.83 | KMT2A (0.49) | KMT2ATDP1ALDH1A1MAPTMEN1 | |
| SCHEMBL12311334 | 0.74 | KMT2A (0.54) | KMT2ATDP1ALDH1A1MAPTCYP2D6 | |
| SCHEMBL16975882 | 0.74 | NPSR1 (0.56) | KMT2ATDP1ALDH1A1MAPTCYP2D6 | |
| SCHEMBL5758878 | 0.74 | GRIN2B (0.50) | KMT2AHTR2AALDH1A1MAPTCYP2D6 | |
| SCHEMBL6008687 | 0.73 | HTR2A (0.47) | KMT2AHTR2AKCNH2ALDH1A1MAPT | |
| SCHEMBL5754844 | 0.72 | KCNH2 (0.60) | HTR2AKCNH2CYP2D6KDM4ECYP1A2 | |
| SCHEMBL5758044 | 0.71 | KCNH2 (0.62) | HTR2AKCNH2CYP2D6KDM4ECYP1A2 | |
| SCHEMBL4395372 | 0.71 | KMT2A (0.55) | KMT2ATDP1HTR2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | claimed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | claimed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | claimed |
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | disclosed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | disclosed |