Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29920738 | 0.97 | — | — | |
| SCHEMBL16868 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL30408604 | 0.95 | — | — | |
| Hydrochloric Acid SCHEMBL5121013 | 0.95 | — | — | |
| Cyanide SCHEMBL28324111 | 0.90 | NOS3 (0.86) | — | |
| Trimethylammonium SCHEMBL27412233 | 0.90 | NOS3 (0.86) | — | |
| Trimethylammonium SCHEMBL27431681 | 0.88 | NOS3 (0.82) | — | |
| Acetic Acid SCHEMBL29112827 | 0.84 | NOS3 (0.75) | — | |
| Formic Acid SCHEMBL28050861 | 0.84 | NOS3 (0.75) | — | |
| SCHEMBL4019673 | 0.81 | NOS3 (0.69) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7148242-B2 | N-formyl hydroxylamine compounds, compositions and methods of use | NOVARTIS AG (CH) | 2006-12-12 | — | — | US | disclosed |
| EP-1401828-B1 | N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF | VICURON PHARM INC (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-1401828-A1 | N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF | Vicuron Pharmaceuticals, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| US-20030045479-A1 | Novel N-formyl hydroxylamine compounds, compositions and methods of use | VICURON HOLDINGS LLC | 2003-03-06 | — | — | US | disclosed |
| WO-2002102790-A1 | N-FORMYL HYDROXYLAMINE COMPOUNDS AS INHIBITORS OF PDF | VICURON PHARMACEUTICALS INC. (US) | 2002-12-27 | — | — | WO | disclosed |
| EP-0091790-B1 | PROCESS FOR PREPARING 2-ALKYLAMINO- AND 2-AMINO-5-ALKYLPYRIDINES | REILLY INDUSTRIES, INC. (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0091790-A2 | Process for preparing 2-alkylamino- and 2-amino-5-alkylpyridines | REILLY INDUSTRIES, INC. (US) | 1983-10-19 | — | — | EP | disclosed |
| US-4405790-A | FROM 3-ALKYLPYRIDINE; SODIUM ALKYLAMIDE | REILLY TAR & CHEMICAL CORP. (US) | 1983-09-20 | — | — | US | disclosed |