Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.78 |
| ▸ | BRD4 | O60885 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL5756262 | 0.96 | OPRM1 (0.73) | OPRM1BRD4HTR1AHTR1DHTR1B | |
| SCHEMBL5754694 | 0.93 | OPRM1 (0.83) | OPRM1BRD4OPRD1OPRK1KCNH2 | |
| SCHEMBL5757038 | 0.90 | OPRM1 (0.75) | OPRM1BRD4OPRD1OPRK1KCNH2 | |
| SCHEMBL5757308 | 0.90 | OPRM1 (0.81) | OPRM1BRD4OPRD1OPRK1KCNH2 | |
| SCHEMBL5753484 | 0.88 | OPRM1 (1.00) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL5756134 | 0.88 | OPRM1 (0.59) | OPRM1BRD4OPRD1OPRK1KCNH2 | |
| Hydrochloric Acid SCHEMBL5756166 | 0.87 | OPRM1 (0.98) | OPRM1OPRD1OPRK1KCNH2 | |
| Acetic Acid SCHEMBL5755135 | 0.87 | OPRM1 (0.75) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL5759759 | 0.86 | OPRM1 (0.81) | OPRM1OPRD1OPRK1KCNH2 | |
| SCHEMBL5755805 | 0.85 | OPRM1 (0.80) | OPRM1OPRD1OPRK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140828-B1 | 3-AZABICYCLO¬3.1.0|HEXANE DERIVATIVES AS OPIATE RECEPTORS LIGANDS | PFIZER LTD (GB) | 2006-08-09 | — | — | EP | claimed |