Oxalic Acid

SCHEMBL5758701

COc1cccc2sc([C@@H]3CCN(C[C@H](O)COc4cccc5[nH]c(C)cc45)[C@H](C)C3)cc12.O=C(O)C(=O)O

nearest known ligand 0.93

Known targets — ChEMBL curated mechanism

The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

	gene	UniProt	supporting neighbours	confidence
▸	SLC6A4 known ✓	P31645	7/20	0.93

▸	HTR1A	P08908	18/20	0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
Oxalic Acid SCHEMBL5759517	1.00	HTR1A (0.93)	HTR1ASLC6A4
Oxalic Acid SCHEMBL5760173	1.00	HTR1A (0.93)	HTR1ASLC6A4
Oxalic Acid SCHEMBL6837041	1.00	HTR1A (0.93)	HTR1ASLC6A4
Oxalic Acid SCHEMBL5761519	1.00	HTR1A (0.93)	HTR1ASLC6A4
SCHEMBL5761018	0.96	HTR1A (1.00)	HTR1ASLC6A4
SCHEMBL5761557	0.96	HTR1A (1.00)	HTR1ASLC6A4
Hydrochloric Acid SCHEMBL5762756	0.96	HTR1A (0.98)	HTR1ASLC6A4
Oxalic Acid SCHEMBL5760307	0.94	HTR1A (0.93)	HTR1ASLC6A4
Oxalic Acid SCHEMBL5758929	0.94	HTR1A (0.93)	HTR1ASLC6A4
Oxalic Acid SCHEMBL5759339	0.94	HTR1A (0.93)	HTR1ASLC6A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-1242411-B1	INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION AND ANXIETY	LILLY CO ELI (US)	2006-03-08	—	—	EP	disclosed