Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 8/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | LMNA | P02545 | 5/20 | 0.37 |
| ▸ | PGR | P06401 | 3/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758525 | 0.85 | KDM4E (0.72) | KDM4EALDH1A1MAPK1NR3C1HIF1A | |
| SCHEMBL5757332 | 0.83 | KDM4E (0.56) | KDM4ENR3C1HIF1ACYP3A4LMNA | |
| SCHEMBL5935168 | 0.83 | KDM4E (0.56) | KDM4ENR3C1HIF1ACYP3A4LMNA | |
| SCHEMBL15167259 | 0.83 | KDM4E (0.56) | KDM4ENR3C1HIF1ACYP3A4LMNA | |
| SCHEMBL9717259 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1MAPK1NR3C1HIF1A | |
| SCHEMBL9737529 | 0.76 | KDM4E (0.50) | KDM4ENR3C1HIF1ACYP3A4LMNA | |
| SCHEMBL5650907 | 0.75 | KDM4E (0.57) | KDM4ENR3C1HIF1ACYP3A4LMNA | |
| SCHEMBL5943277 | 0.74 | KDM4E (0.80) | KDM4EALDH1A1MAPK1NR3C1HIF1A | |
| SCHEMBL5943274 | 0.74 | KDM4E (0.80) | KDM4EALDH1A1MAPK1NR3C1HIF1A | |
| SCHEMBL9524808 | 0.73 | KDM4E (0.47) | KDM4ENR3C1HIF1ACYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060252926-A1 | Process for the preparation of pregnanes | SICOR, INC. | 2006-11-09 | — | — | US | disclosed |
| EP-1474435-B1 | PROCESS FOR THE PREPARATION OF 6-ALPHA FLUORINATED PREGNANES | SICOR INC (US) | 2006-02-22 | — | — | EP | disclosed |
| EP-1474435-A1 | PROCESS FOR THE PREPARATION OF PREGNANES | Sicor Inc. (US) | 2004-11-10 | — | — | EP | disclosed |
| WO-2004052911-A1 | PROCESS FOR THE PREPARATION OF PREGNANES | SICOR INC. (US) | 2004-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060252926-A1 | Process for the preparation of pregnanes | CYP17A1, CYP21A2, NR5A1 | KDM4E 4594/4885ALDH1A1 1775/4885MAPK1 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.