Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4809614 | 0.79 | APP (0.39) | APPSLC22A2SLC22A1SLC22A3ESR1 | |
| SCHEMBL25893853 | 0.79 | PDE2A (0.50) | APPMEN1KMT2ASLC22A2SLC22A1 | |
| SCHEMBL10963 | 0.79 | APP (0.39) | APPMEN1KMT2AESR1ESR2 | |
| Iodide SCHEMBL25236695 | 0.77 | PDE2A (0.48) | APPMEN1KMT2ASLC22A2SLC22A1 | |
| SCHEMBL10553790 | 0.77 | TSHR (0.55) | MEN1KMT2ASLC22A2SLC22A1SLC22A3 | |
| SCHEMBL7975886 | 0.77 | ESR1 (0.59) | MEN1KMT2AESR1ESR2LMNA | |
| SCHEMBL26687541 | 0.77 | KCNN4 (0.48) | MEN1KMT2ALMNACYP3A4PDE2A | |
| SCHEMBL3855932 | 0.75 | MEN1 (0.65) | MEN1KMT2ATSHRSLC6A2SLC6A4 | |
| SCHEMBL7129323 | 0.75 | APP (0.37) | APPMEN1KMT2ASLC22A2SLC22A1 | |
| Hydrochloric Acid SCHEMBL6457601 | 0.75 | ESR1 (0.56) | MEN1KMT2AESR1ESR2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292593-B1 | 2-(3,5-DISUBSTITUTED-4-PYRIDYL)-4-(THIENYL, THIAZOLYL OR ARYLPHENYL)-1,3-OXAZOLINE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2006-06-07 | — | — | EP | disclosed |
| US-6924298-B2 | 2-(3,5-Disubstituted-4-pyridyl)-4-(thienyl, thiazolyl or arylphenyl)-1,3-oxazoline compounds | DOW AGROSCIENCES LLC (US) | 2005-08-02 | — | — | US | disclosed |
| US-20040006108-A1 | 2-(3,5-Disubstituted-4-pyridyl)-4-(thienyl, thiazolyl or arylphenyl)-1,3-oxazoline compounds | TISDELL FRANCIS EUGENE (US) | 2004-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040006108-A1 | 2-(3,5-Disubstituted-4-pyridyl)-4-(thienyl, thiazolyl or arylphenyl)-1,3-oxazoline compounds | TARS2, TTL, TARS1 | APP 3682/4885MEN1 3109/4885KMT2A 1395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.