Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL933985 | 0.74 | NAPRT (0.46) | — | |
| SCHEMBL4540614 | 0.73 | CYP11B1 (0.39) | — | |
| SCHEMBL1654148 | 0.73 | KMT2A (0.41) | TDP1 | |
| SCHEMBL3411109 | 0.71 | POLB (0.44) | — | |
| SCHEMBL1651982 | 0.70 | LMNA (0.47) | TDP1 | |
| SCHEMBL6982496 | 0.69 | GSK3B (0.45) | — | |
| SCHEMBL3605168 | 0.69 | FFAR1 (0.34) | — | |
| SCHEMBL1651006 | 0.68 | HCAR2 (0.46) | — | |
| SCHEMBL30567639 | 0.68 | MAPK1 (0.40) | TDP1 | |
| SCHEMBL5762975 | 0.68 | MAPK1 (0.40) | TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725101-A1 | 2-PYRIDINYL [7-(SUBSTITUTED-PYRIDIN-4-YL) PYRAZOLO[1,5-A] PYRIMIDIN-3-YL] METHANONES | DOV Pharmaceutical Inc. (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005084439-A1 | 2-PYRIDINYL[7-(SUBSTITUTED-PYRIDIN-4-YL) PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]METHANONES | DOV PHARMACEUTICAL, INC. (US) | 2005-09-15 | — | — | WO | disclosed |