Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 16/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 9/20 | 0.49 |
| ▸ | MMP13 | P45452 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 3/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydroxyamine SCHEMBL7155378 | 0.98 | MMP1 (0.47) | MMP1ADAM17MMP13MMP3MMP7 | |
| SCHEMBL7450392 | 0.93 | MMP1 (0.57) | MMP1ADAM17MMP13MMP3MMP7 | |
| SCHEMBL5760537 | 0.93 | MMP1 (0.57) | MMP1ADAM17MMP13MMP3MMP7 | |
| SCHEMBL7155386 | 0.92 | MMP1 (0.46) | MMP1ADAM17MMP13MMP3MMP7 | |
| Hydroxyamine SCHEMBL7156722 | 0.91 | MMP1 (0.54) | MMP1ADAM17MMP13MMP3MMP9 | |
| SCHEMBL7155381 | 0.88 | MMP1 (0.47) | MMP1ADAM17MMP13MMP3MMP7 | |
| SCHEMBL27573428 | 0.87 | MMP1 (0.49) | MMP1ADAM17MMP13MMP3MMP7 | |
| SCHEMBL5759833 | 0.86 | MMP1 (0.48) | MMP1ADAM17MMP13MMP3MMP7 | |
| SCHEMBL5758094 | 0.85 | MMP1 (0.61) | MMP1ADAM17MMP13MMP3 | |
| SCHEMBL7156717 | 0.84 | MMP1 (0.53) | MMP1ADAM17MMP13MMP3MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1104403-B1 | HYDROXY PIPECOLATE HYDROXAMIC ACID DERIVATIVES AS MMP INHIBITORS | PFIZER PROD INC (US) | 2006-05-10 | — | — | EP | claimed |