Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 4/20 | 0.80 |
| ▸ | HTR1A | P08908 | 18/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL5761126 | 1.00 | HTR1A (0.83) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5761102 | 1.00 | HTR1A (0.83) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5761041 | 1.00 | HTR1A (0.83) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5762774 | 0.94 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5762477 | 0.94 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5760154 | 0.94 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5761386 | 0.94 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5759524 | 0.92 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5759022 | 0.92 | HTR1A (0.93) | HTR1ASLC6A4 | |
| Oxalic Acid SCHEMBL5761310 | 0.92 | HTR1A (0.93) | HTR1ASLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7144898-B2 | Indole derivatives for the treatment of depression and anxiety | ELI LILLY AND COMPANY (US) | 2006-12-05 | — | — | US | disclosed |
| EP-1242411-B1 | INDOLE DERIVATIVES FOR THE TREATMENT OF DEPRESSION AND ANXIETY | LILLY CO ELI (US) | 2006-03-08 | — | — | EP | disclosed |