Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | QPCT | Q16769 | 1/20 | 0.50 |
| ▸ | ATP4A | P20648 | 3/20 | 0.48 |
| ▸ | ATP4B | P51164 | 3/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5759974 | 0.97 | HMOX1 (0.62) | HMOX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5762143 | 0.95 | FFAR1 (0.58) | HMOX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5761107 | 0.93 | HMOX1 (0.52) | HMOX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5760668 | 0.92 | FFAR1 (0.59) | HMOX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5759324 | 0.90 | HMOX1 (0.53) | HMOX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5761656 | 0.90 | FFAR1 (0.55) | HMOX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5756550 | 0.89 | HMOX1 (0.57) | HMOX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5758811 | 0.89 | KDM4E (0.56) | HMOX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5763118 | 0.89 | HMOX1 (0.50) | HMOX1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5758931 | 0.88 | FFAR1 (0.50) | HMOX1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1270571-B1 | Heterocyclic compounds, their production and use | TAKEDA PHARMACEUTICAL (JP) | 2006-09-06 | — | — | EP | disclosed |
| EP-1270571-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6211215-B1 | AROMATIC HETEROCYCLIC COMPOUND WITH AZOLE COMPOUND | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-04-03 | — | — | US | disclosed |