Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Silver SCHEMBL2571872 | 0.92 | ALDH1A1 (0.31) | ALDH1A1MEN1TSHRKMT2ATP53 | |
| Potassium Ion SCHEMBL29170921 | 0.92 | ALDH1A1 (0.31) | ALDH1A1MEN1TSHRKMT2ATP53 | |
| SCHEMBL5022370 | 0.92 | ALDH1A1 (0.40) | ALDH1A1MEN1TSHRKMT2ATP53 | |
| SCHEMBL2524418 | 0.92 | ALDH1A1 (0.31) | ALDH1A1MEN1TSHRKMT2ATP53 | |
| Lithium Ion SCHEMBL2523019 | 0.92 | ALDH1A1 (0.31) | ALDH1A1MEN1TSHRKMT2ATP53 | |
| SCHEMBL2521151 | 0.92 | ALDH1A1 (0.31) | ALDH1A1MEN1TSHRKMT2ATP53 | |
| Sulfuric Acid SCHEMBL7170418 | 0.78 | TP53 (0.39) | ALDH1A1MEN1TSHRKMT2ATP53 | |
| Ammonia Solution, Strong SCHEMBL5760494 | 0.77 | MEN1 (0.37) | ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL833093 | 0.75 | — | — | |
| Zinc Ion SCHEMBL30963670 | 0.75 | ALDH1A1 (0.31) | ALDH1A1MEN1TSHRKMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446404-B1 | ROSIGLITAZONE EDISYLATES AND THEIR USE AS ANTIDIABETICS | SMITHKLINE BEECHAM PLC (GB) | 2006-06-14 | — | — | EP | disclosed |
| US-20050107440-A1 | Rosiglitazone edisylates and their use as antidiabetics | SMITHKLINE BEECHAM P.L.C. (GB) | 2005-05-19 | — | — | US | disclosed |
| EP-1446404-A1 | ROSIGLITAZONE EDISYLATES AND THEIR USE AS ANTIDIABETICS | SMITHKLINE BEECHAM PLC (GB) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003045947-A1 | ROSIGLITAZONE EDISYLATES AND THEIR USE AS ANTIDIABETICS | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-06-05 | — | — | WO | disclosed |