Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | SLC27A2 | O14975 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761084 | 1.00 | PDK2 (0.50) | PDK2ALDH1A1MAPK1PTPRCOPRM1 | |
| SCHEMBL5763937 | 0.95 | PDK2 (0.46) | PDK2ALDH1A1MAPK1PTPRCOPRM1 | |
| SCHEMBL29602609 | 0.91 | PDK2 (0.58) | PDK2ALDH1A1MAPK1PTPRCOPRM1 | |
| SCHEMBL783450 | 0.91 | PDK2 (0.58) | PDK2ALDH1A1MAPK1PTPRCOPRM1 | |
| SCHEMBL29399278 | 0.91 | PDK2 (0.58) | PDK2ALDH1A1MAPK1PTPRCOPRM1 | |
| SCHEMBL29397249 | 0.91 | PDK2 (0.58) | PDK2ALDH1A1MAPK1PTPRCOPRM1 | |
| SCHEMBL996751 | 0.91 | PDK2 (0.58) | PDK2ALDH1A1MAPK1PTPRCOPRM1 | |
| SCHEMBL783463 | 0.91 | PDK2 (0.58) | PDK2ALDH1A1MAPK1PTPRCOPRM1 | |
| SCHEMBL29574412 | 0.91 | PDK2 (0.58) | PDK2ALDH1A1MAPK1PTPRCOPRM1 | |
| SCHEMBL29511719 | 0.91 | PDK2 (0.58) | PDK2ALDH1A1MAPK1PTPRCOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1690847-B1 | pi-conjugated compound having cardo structure, process for the preparation thereof and use thereof | TOSOH CORP (JP) | 2016-06-22 | — | — | EP | disclosed |
| US-20060186797-A1 | Pi-conjugated compound having cardo structure, process for preparing same and use of same | TOSOH CORPORATION (JP) | 2006-08-24 | — | — | US | disclosed |
| EP-1690847-A1 | pi-Conjugated compound having cardo structure, process for the preparation thereof and use thereof | Tosoh Corporation (JP) | 2006-08-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060186797-A1 | Pi-conjugated compound having cardo structure, process for preparing same and use of same | ARL1, TERB1, LEO1 | PDK2 3990/4885ALDH1A1 2247/4885MAPK1 1410/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.