Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 4/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 4/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5761854 | 0.91 | NPC1 (0.40) | HDAC3NPC1RAB9A | |
| SCHEMBL5762678 | 0.90 | HPGD (0.39) | NPC1RAB9A | |
| SCHEMBL5762545 | 0.89 | HPGD (0.38) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL5760247 | 0.89 | CNR1 (0.37) | FFAR1MAPTROCK2KDM4EMEN1 | |
| SCHEMBL6888684 | 0.86 | FFAR1 (0.44) | PLAAT5PLAAT4PLAAT3PLAAT2FFAR1 | |
| SCHEMBL5763387 | 0.83 | PSMB5 (0.39) | LMNAFFAR1MAPTROCK2NPC1 | |
| SCHEMBL5763139 | 0.81 | PPARG (0.50) | OPRM1OPRD1OPRK1 | |
| SCHEMBL1750119 | 0.81 | PPARG (0.50) | OPRM1OPRD1OPRK1 | |
| SCHEMBL1749756 | 0.80 | PPARG (0.43) | TP53LMNAOPRM1OPRD1OPRK1 | |
| Hydrochloric Acid SCHEMBL1750383 | 0.80 | PPARG (0.49) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638964-A1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113331-A1 | NOVEL COMPOUNDS THAT MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-29 | — | — | WO | disclosed |