Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762678 | 0.99 | HPGD (0.39) | HPGDNPC1ALDH1A1RAB9AADRB2 | |
| SCHEMBL5761854 | 0.96 | NPC1 (0.40) | HPGDNPC1ALDH1A1RAB9AATM | |
| SCHEMBL68137 | 0.91 | SYK (0.41) | HPGDNPC1ALDH1A1RAB9AADRB2 | |
| SCHEMBL5762989 | 0.89 | TP53 (0.37) | NPC1RAB9AMEN1KMT2A | |
| SCHEMBL67830 | 0.87 | HPGD (0.45) | HPGDNPC1ALDH1A1RAB9AADRB2 | |
| SCHEMBL5760247 | 0.83 | CNR1 (0.37) | HPGDALDH1A1MEN1KMT2A | |
| SCHEMBL5762390 | 0.83 | NPC1 (0.44) | HPGDNPC1ALDH1A1RAB9AATM | |
| SCHEMBL5762596 | 0.80 | PPARG (0.37) | HPGDNPC1ALDH1A1RAB9AP2RY12 | |
| SCHEMBL5761221 | 0.80 | HPGD (0.35) | HPGDNPC1ALDH1A1RAB9AADRB2 | |
| SCHEMBL5763337 | 0.80 | ALDH1A1 (0.39) | HPGDNPC1ALDH1A1RAB9AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638964-A1 | NOVEL COMPOUNDS THAT MODULATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004113331-A1 | NOVEL COMPOUNDS THAT MODULATE PPARϜ TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-12-29 | — | — | WO | disclosed |