Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5764671 | 0.82 | — | — | |
| SCHEMBL5764595 | 0.74 | DGAT1 (0.30) | — | |
| SCHEMBL15904085 | 0.65 | HSP90AB1 (0.41) | GAA | |
| SCHEMBL8725001 | 0.63 | HSP90AB1 (0.45) | GAA | |
| SCHEMBL12819534 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL4410477 | 0.62 | HSP90AB1 (0.43) | GAA | |
| SCHEMBL14306903 | 0.60 | MAPK1 (0.32) | — | |
| SCHEMBL22011296 | 0.59 | KDM4E (0.35) | GAA | |
| SCHEMBL1018739 | 0.57 | — | — | |
| SCHEMBL2686771 | 0.57 | CDK2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091738-B1 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2006-12-06 | — | — | EP | disclosed |
| US-6384041-B1 | ANTIINFLAMMATORY AGENT, TREATMENT OF SHOCK AND ENZYME INHIBITORS | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |