Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 14/20 | 0.36 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2210863 | 1.00 | PTGER4 (0.36) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2210470 | 1.00 | PTGER4 (0.36) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2211406 | 0.83 | PTGER4 (0.43) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2212480 | 0.83 | PTGER4 (0.43) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2211412 | 0.83 | PTGER4 (0.43) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2212489 | 0.83 | PTGER4 (0.43) | PTGER4PTGER3PTGER2 | |
| SCHEMBL12288900 | 0.77 | PTGER3 (0.47) | PTGER4PTGER3PTGER2 | |
| SCHEMBL2241761 | 0.77 | PTGER3 (0.47) | PTGER4PTGER3PTGER2 | |
| SCHEMBL1555462 | 0.77 | PTGER4 (0.40) | PTGER4PTGER3PTGER2 | |
| SCHEMBL3672265 | 0.73 | PTGER4 (0.37) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1613621-A1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | Merck Frosst Canada Ltd. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004085430-A1 | PROSTAGLANDIN ANALOGS AS EP4 RECEPTOR AGONISTS | MERCK FROSST CANADA LTD. (CA) | 2004-10-07 | — | — | WO | disclosed |