Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793193 | 0.92 | HPGD (0.44) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5077087 | 0.80 | HPGD (0.48) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5079495 | 0.80 | HPGD (0.48) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL3159889 | 0.80 | HPGD (0.48) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL4699112 | 0.79 | HPGD (0.47) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL10274190 | 0.79 | HPGD (0.54) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5076062 | 0.79 | MRGPRX4 (0.47) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL2127531 | 0.79 | MRGPRX4 (0.47) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL2127040 | 0.79 | HPGD (0.47) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5079499 | 0.79 | HPGD (0.47) | HPGDMAPK1KMT2ATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638962-A2 | SUBSTITUTED OXYARENES UND DEREN VERWENDUNG ZUR BEKÄMPFUNG VON SCHÄDLINGEN | Bayer CropScience AG (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004099197-A2 | SUBSTITUTED OXYARENES, AND USE THEREOF FOR CONTROLLING PESTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2004-11-18 | — | — | WO | disclosed |