Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 17/20 | 0.83 |
| ▸ | ACP1 | P24666 | 2/20 | 0.45 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730825 | 0.86 | PTPN1 (0.93) | PTPN1EYA3 | |
| SCHEMBL3864688 | 0.86 | PTPN1 (0.71) | PTPN1EYA3 | |
| SCHEMBL4264241 | 0.81 | PTPN1 (0.70) | PTPN1 | |
| SCHEMBL3863449 | 0.81 | PTPN1 (0.59) | PTPN1ACP1 | |
| SCHEMBL7855340 | 0.80 | PTPN1 (0.82) | PTPN1EYA3 | |
| SCHEMBL4461358 | 0.80 | PTPN1 (0.64) | PTPN1ACP1EYA3 | |
| SCHEMBL3864502 | 0.79 | PTPN1 (0.61) | PTPN1EYA3 | |
| SCHEMBL4474980 | 0.79 | PTPN1 (0.63) | PTPN1ACP1EYA3 | |
| SCHEMBL4270758 | 0.78 | PTPN1 (0.59) | PTPN1EYA3 | |
| SCHEMBL4270762 | 0.78 | PTPN1 (0.59) | PTPN1EYA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1620420-A2 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099168-A2 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | disclosed |