Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.50 |
| ▸ | MMP2 | P08253 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6002580 | 1.00 | KDM1A (0.51) | KDM1AMAOAMAOBRCOR1MMP2 | |
| SCHEMBL5762893 | 0.82 | NPC1 (0.49) | KDM1AMAOAMAOBRCOR1MMP2 | |
| SCHEMBL6003765 | 0.80 | KDM1A (0.43) | KDM1AMAOAMAOBRCOR1TP53 | |
| SCHEMBL6607260 | 0.80 | NPC1 (0.55) | KDM1AMAOAMAOBRCOR1TP53 | |
| SCHEMBL10598558 | 0.73 | POLB (0.69) | KDM1AMAOAMAOBRCOR1TP53 | |
| Benzyl Phenylcarbamate SCHEMBL1222943 | 0.73 | POLB (0.78) | KDM1AMAOAMAOBRCOR1TP53 | |
| SCHEMBL4187427 | 0.73 | POLB (0.61) | KDM1AMAOAMAOBRCOR1TP53 | |
| SCHEMBL9080564 | 0.72 | POLB (0.68) | KDM1AMAOAMAOBRCOR1TP53 | |
| SCHEMBL2175244 | 0.72 | POLB (0.53) | KDM1AMAOAMAOBRCOR1MMP2 | |
| SCHEMBL16946758 | 0.72 | POLB (0.59) | KDM1AMAOAMAOBRCOR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1656357-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | Merck & Co., Inc. (US) | 2006-05-17 | — | — | EP | disclosed |
| WO-2005005399-A1 | OXAZOLIDINONE ANTIBIOTICS AND DERIVATIVES THEREOF | MERCK & CO., INC. (US) | 2005-01-20 | — | — | WO | disclosed |