Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propane SCHEMBL28832596 | 0.77 | — | — | |
| Formamide SCHEMBL8826010 | 0.76 | MEN1 (0.32) | MEN1POLBKMT2A | |
| Formic Acid SCHEMBL5764681 | 0.75 | ALDH1A1 (0.35) | MEN1POLBKMT2AALDH1A1MAPK1 | |
| Formic Acid SCHEMBL27585558 | 0.75 | ALDH1A1 (0.35) | MEN1POLBKMT2AALDH1A1MAPK1 | |
| Formic Acid Methyl Ester SCHEMBL28191844 | 0.74 | — | — | |
| Ammonia Solution, Strong SCHEMBL28460951 | 0.73 | ALDH1A1 (0.36) | MEN1POLBKMT2AALDH1A1MAPK1 | |
| Ammonia Solution, Strong SCHEMBL3635387 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL22129991 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL459043 | 0.73 | — | — | |
| Ammonia Solution, Strong SCHEMBL3139103 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7019147-B1 | Benzimidazole derivatives useful as antiproliferative agents | PFIZER INC. (US) | 2006-03-28 | — | — | US | disclosed |
| EP-1235825-B1 | NOVEL BENZOIMIDAZOLE DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | PFIZER PROD INC (US) | 2006-01-25 | — | — | EP | disclosed |
| EP-1235825-A1 | NOVEL BENZOIMIDAZOLE DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | Pfizer Products Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001040217-A1 | NOVEL BENZOIMIDAZOLE DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | PFIZER PRODUCTS INC. (US) | 2001-06-07 | — | — | WO | disclosed |