Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.43 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.43 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.43 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.43 |
| ▸ | DHFR | P00374 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5793380 | 0.91 | ALDH1A1 (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CDHFR | |
| SCHEMBL5767392 | 0.90 | CA1 (0.42) | CACNA1FCACNA1DCACNA1SCACNA1CDHFR | |
| SCHEMBL5793568 | 0.89 | ALDH1A1 (0.38) | CACNA1FCACNA1DCACNA1SCACNA1CDHFR | |
| SCHEMBL5765288 | 0.88 | ALDH1A1 (0.44) | CACNA1FCACNA1DCACNA1SCACNA1CDHFR | |
| SCHEMBL5911496 | 0.88 | ALDH1A1 (0.39) | CACNA1FCACNA1DCACNA1SCACNA1CDHFR | |
| SCHEMBL5766350 | 0.87 | ALDH1A1 (0.38) | CACNA1FCACNA1DCACNA1SCACNA1CDHFR | |
| SCHEMBL5794068 | 0.86 | ALDH1A1 (0.42) | CACNA1FCACNA1DCACNA1SCACNA1CDHFR | |
| SCHEMBL5911215 | 0.86 | ALDH1A1 (0.37) | CACNA1FCACNA1DCACNA1SCACNA1CDHFR | |
| SCHEMBL5911640 | 0.86 | ALDH1A1 (0.37) | CACNA1FCACNA1DCACNA1SCACNA1CMAPK1 | |
| SCHEMBL5792331 | 0.80 | CACNA1F (0.49) | CACNA1FCACNA1DCACNA1SCACNA1CMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1893910-A | Cyclic siloxane compositions for active ingredient release | GEN ELECTRIC (US) | 2007-01-10 | — | — | CN | claimed |
| CN-1469860-A | Aza-amino acid derivatives (factor XA-inhibitors 15) | Ĭ��ר���ɷ�����˾ | 2004-01-21 | — | — | CN | claimed |
| CN-106029064-A | Therapeutic compounds and compositions | 艾克赛特赫拉制药有限责任公司 | 2016-10-12 | — | — | CN | disclosed |
| CN-105992768-A | Imidazopyridazine compounds useful as modulators of il-12, il-23 and/or ifn alpha responses | 百时美施贵宝公司 | 2016-10-05 | — | — | CN | disclosed |
| CN-105294701-A | Cyclic P1 linkers as factor XIA inhibitors | BRISTOL MYERS SQUIBB CO | 2016-02-03 | — | — | CN | disclosed |
| CN-105228996-A | Tetrahydroisoquinolines containing substituted azoles as factor xia inhibitors | BRISTOL MYERS SQUIBB CO | 2016-01-06 | — | — | CN | disclosed |
| CN-1882701-B | Size-controlled macromole | POSCO (KR) | 2015-11-25 | — | — | CN | disclosed |
| CN-103702999-B | Cyclic P1 linkers as factor XIA inhibitors | BRISTOL-MYERS SQUIBB CO. (US) | 2015-11-25 | — | — | CN | disclosed |
| CN-104774175-A | Labeled inhibitors of prostate specific membrane antigen (PSMA), biological evaluation, and use as imaging agents | UNIV JOHNS HOPKINS | 2015-07-15 | — | — | CN | disclosed |
| CN-101784192-B | Inhibitors of labeled Prostate Specific Membrane Antigen (PSMA), biological evaluation and use as imaging agents | UNIV JOHNS HOPKINS | 2015-03-18 | — | — | CN | disclosed |
| CN-102026996-B | Pyridazine derivatives as factor XIA inhibitors | BRISTOL MYERS SQUIBB CO | 2015-01-07 | — | — | CN | disclosed |
| CN-1036959-A | Cephem compounds and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1989-11-08 | — | — | CN | disclosed |
| US-4851422-A | Antibiotic 2-(3-oxo-2-isoxazolidinyl)-5-oxo-2-tetrahydrofuran-carboxylates | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-07-25 | — | — | US | disclosed |
| CN-1033628-A | Imidazopyridine compound and preparation method thereof | FUJISAWA PHARMACEUTIAL CO LTD (JP) | 1989-07-05 | — | — | CN | disclosed |
| CN-1032540-A | Cephem compound and preparation method thereof | FUJISAWA PHARMACEUTICAL CO (JP) | 1989-04-26 | — | — | CN | disclosed |
| CN-87107938-A | 3-pyrrolidyl sulfo--1-azabicyclo [3,2,0] hept-2-ene\"-2-formic acid cpds and preparation method thereof | — | 1988-08-10 | — | — | CN | disclosed |
| CN-87104230-A | Different oxazolidinone derivative and production method thereof | — | 1987-12-23 | — | — | CN | disclosed |
| EP-0219923-A1 | Antibiotic derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1987-04-29 | — | — | EP | disclosed |
| CN-86104313-A | The preparation method of Imidazoheterocyclic compounds | — | 1987-03-04 | — | — | CN | disclosed |
| US-4016159-A | BACTERICIDES | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |