Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.36 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6621800 | 0.83 | DRD2 (0.44) | DRD2IDO1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5760995 | 0.81 | DRD2 (0.42) | DRD2IDO1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL5761293 | 0.78 | CNR1 (0.48) | LMNAALDH1A1SMN1; SMN2PKMKMT2A | |
| SCHEMBL5219319 | 0.75 | DRD2 (0.40) | DRD2LMNAALDH1A1SMN1; SMN2TSHR | |
| SCHEMBL6621956 | 0.73 | DRD2 (0.43) | DRD2IDO1LMNAKMT2AGAA | |
| SCHEMBL6620958 | 0.70 | DRD2 (0.46) | DRD2IDO1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30334063 | 0.70 | DRD2 (0.49) | DRD2IDO1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL30334617 | 0.70 | DRD2 (0.49) | DRD2IDO1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3650901 | 0.70 | DRD2 (0.49) | DRD2IDO1LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3660216 | 0.69 | DRD2 (0.46) | DRD2IDO1LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663966-A1 | 1,3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES | Novartis AG (CH) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026113-A1 | 1, 3-DISUBSTITUTED AZETIDINE DERIVATIVES FOR USE AS CCR-3 RECEPTOR ANTAGONISTS IN THE TREATMENT OF INFLAMMATORY AND ALLERGIC DISEASES | NOVARTIS AG (CH) | 2005-03-24 | — | — | WO | disclosed |