SCHEMBL57649

SCHEMBL57649

NCc1ccc2c(c1)OCO2

nearest known ligand 0.71

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 4/20 0.71
SLC6A4 P31645 3/20 0.63
SLC6A2 P23975 2/20 0.59
SLC6A3 Q01959 2/20 0.59
CYP3A4 P08684 5/20 0.58
CYP1A2 P05177 2/20 0.58
MAPT P10636 1/20 0.58
CYP2D6 P10635 2/20 0.55
CMA1 P23946 1/20 0.55
ALDH1A1 P00352 2/20 0.53
GAA P10253 2/20 0.53
CYP2C19 P33261 1/20 0.53
MIF P14174 1/20 0.53
CALM1 P0DP23 1/20 0.51
ALOX12 P18054 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29463278 1.00 TAAR1 (0.71) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
Ammonia Solution, Strong SCHEMBL2661345 0.98 TAAR1 (0.69) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
Hydrochloric Acid SCHEMBL5013418 0.98 TAAR1 (0.69) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
Water SCHEMBL25339785 0.98 TAAR1 (0.69) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
Propane SCHEMBL7393280 0.94 TAAR1 (0.65) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
Ethylene Glycol SCHEMBL8204876 0.92 TAAR1 (0.62) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
Isopropylamine SCHEMBL3559831 0.91 TAAR1 (0.70) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
1,3-Propanediol SCHEMBL19326720 0.89 TAAR1 (0.59) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
SCHEMBL5211220 0.89 TAAR1 (0.59) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4
Acetic Acid SCHEMBL28970009 0.88 CYP3A4 (0.62) TAAR1SLC6A4SLC6A2SLC6A3CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2950 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010895-A Preparation method of N-hydroxyethyl-3, 4-methylenedioxy aniline 浙江鼎龙科技股份有限公司 2026-05-12 CN claimed
US-20250145472-A1 METHOD FOR GENERATING CARBON DIOXIDE KOBE GAKUIN EDUCATIONAL FOUNDATION (JP) 2025-05-08 US claimed
CN-119836121-A Perovskite solar cell based on piperonyl amine additive and preparation method thereof 华北电力大学 2025-04-15 CN claimed
EP-4480568-A1 METHOD FOR GENERATING CARBON DIOXIDE Kobe Gakuin Educational Foundation (JP) 2024-12-25 EP claimed
CN-118530208-A Piper-amid compounds and application thereof 扬州大学 2024-08-23 CN claimed
CN-118440109-A Method for synthesizing low-threshold perovskite laser material by taking piperonyl amine as ligand 天津大学 2024-08-06 CN claimed
CN-118203664-A Composition containing at least one natural or synthetic N-alkylamide as active substance and method for producing same 埃利奥诺公司 2024-06-18 CN claimed
CN-118126017-A Preparation method of 3, 4-methylenedioxy-phenylglycolic acid 山东新和成药业有限公司 2024-06-04 CN claimed
CN-117982471-A Application of orange yellow piperamide in preparation of medicine for treating acute kidney injury 安徽医科大学 2024-05-07 CN claimed
CN-115925672-B Preparation method of oxolinic acid intermediate 湖北龙翔药业科技股份有限公司 2024-03-22 CN claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0635508-A1 TETRAHYDROPYRIDINE DERIVATIVE HAVING SUBSTITUENTS ON THREE RINGS Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1995-01-25 EP claimed
US-5371247-A Preparation of substituted ethenes FINE ORGANICS LIMITED (GB) 1994-12-06 US claimed
EP-0466733-B1 PREPARATION OF SUBSTITUTED ETHENES FINE ORGANICS LTD (GB) 1994-08-17 EP claimed
EP-0466733-A1 PREPARATION OF SUBSTITUTED ETHENES. FINE ORGANICS LTD (GB) 1992-01-22 EP claimed
US-5030738-A Synthesis of antiulcer compounds JANUS FARMACEUTICI S.R.L. (IT) 1991-07-09 US claimed
WO-1990012002-A1 PREPARATION OF SUBSTITUTED ETHENES FINE ORGANICS LIMITED (GB) 1990-10-18 WO claimed
EP-0269650-A1 SYNTHESIS OF ANTIULCER COMPOUNDS RECORDATI FARMA SRL (IT) 1988-06-08 EP claimed
WO-1987005902-A1 SYNTHESIS OF ANTIULCER COMPOUNDS RECORDATI FARMA SRL (IT) 1987-10-08 WO claimed
US-4224416-A Degradable plastic composition containing amine OWENS-ILLINOIS, INC. (US) 1980-09-23 US claimed