Ethylene Glycol

Ethylene Glycol

SCHEMBL8204876

NCc1ccc2c(c1)OCO2.OCCO

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.62
CYP3A4 P08684 6/20 0.57
CYP2D6 P10635 1/20 0.57
SLC6A4 P31645 2/20 0.56
SLC6A2 P23975 1/20 0.53
SLC6A3 Q01959 1/20 0.53
CYP1A2 P05177 2/20 0.51
ALDH1A1 P00352 2/20 0.51
GAA P10253 2/20 0.51
MAPT P10636 1/20 0.51
CYP2C19 P33261 1/20 0.51
CALM1 P0DP23 2/20 0.50
ALOX12 P18054 1/20 0.50
CMA1 P23946 1/20 0.49
MEN1 O00255 1/20 0.48
LMNA P02545 1/20 0.48
MAPK1 P28482 1/20 0.48
MMP13 P45452 1/20 0.48
KMT2A Q03164 1/20 0.48
MIF P14174 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,3-Propanediol SCHEMBL19326720 0.93 TAAR1 (0.59) TAAR1CYP3A4CYP2D6SLC6A4SLC6A2
SCHEMBL29463278 0.92 TAAR1 (0.71) TAAR1CYP3A4CYP2D6SLC6A4SLC6A2
SCHEMBL57649 0.92 TAAR1 (0.71) TAAR1CYP3A4CYP2D6SLC6A4SLC6A2
Hydrochloric Acid SCHEMBL5013418 0.90 TAAR1 (0.69) TAAR1CYP3A4CYP2D6SLC6A4SLC6A2
Ammonia Solution, Strong SCHEMBL2661345 0.90 TAAR1 (0.69) TAAR1CYP3A4CYP2D6SLC6A4SLC6A2
Water SCHEMBL25339785 0.90 TAAR1 (0.69) TAAR1CYP3A4CYP2D6SLC6A4SLC6A2
Propane SCHEMBL7393280 0.87 TAAR1 (0.65) TAAR1CYP3A4CYP2D6SLC6A4SLC6A2
Acetic Acid SCHEMBL28970009 0.84 CYP3A4 (0.62) TAAR1CYP3A4SLC6A4SLC6A2SLC6A3
Isopropylamine SCHEMBL3559831 0.84 TAAR1 (0.70) TAAR1CYP3A4CYP2D6SLC6A4SLC6A2
SCHEMBL5211220 0.82 TAAR1 (0.59) TAAR1CYP3A4CYP2D6SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6162521-A Fluoropolyether amide lubricants for an information storage system and a method of making the same SEAGATE TECHNOLOGY LLC (US) 2000-12-19 US claimed
US-6162521-A Fluoropolyether amide lubricants for an information storage system and a method of making the same SEAGATE TECHNOLOGY LLC (US) 2000-12-19 US disclosed