Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14573157 | 0.89 | KCNH2 (0.73) | KCNH2 | |
| SCHEMBL5764517 | 0.89 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL5749375 | 0.86 | KCNH2 (0.59) | KCNH2 | |
| SCHEMBL5764668 | 0.84 | KCNH2 (0.53) | KCNH2 | |
| Hydrochloric Acid SCHEMBL6760325 | 0.84 | KCNH2 (0.70) | KCNH2 | |
| SCHEMBL5764918 | 0.83 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL5762645 | 0.83 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL5765930 | 0.81 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL6669043 | 0.80 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL5764847 | 0.79 | KCNH2 (0.48) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392686-B1 | BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2006-10-18 | — | — | EP | claimed |