Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 14/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6666169 | 0.88 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL6667359 | 0.87 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL14573157 | 0.85 | KCNH2 (0.73) | KCNH2 | |
| SCHEMBL6667458 | 0.84 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL6669764 | 0.82 | ALDH1A1 (0.50) | KCNH2 | |
| SCHEMBL5765611 | 0.80 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL5656515 | 0.79 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3250060 | 0.77 | KCNH2 (0.62) | KCNH2 | |
| SCHEMBL6664492 | 0.76 | KCNH2 (0.41) | KCNH2 | |
| Hydrochloric Acid SCHEMBL6760325 | 0.76 | KCNH2 (0.70) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392686-A1 | BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2004-03-03 | — | — | EP | claimed |
| WO-2002096907-A1 | BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-12-05 | — | — | WO | claimed |