Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 6/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.32 |
| ▸ | CALML3 | P27482 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | SDHA | P31040 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3035262 | 1.00 | MAOA (0.41) | MAOAGRIN1GRIN2BMAOBCALML3 | |
| SCHEMBL3035027 | 0.89 | MAOA (0.53) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3046255 | 0.87 | MAOA (0.41) | MAOAGRIN1GRIN2BMAOBCALML3 | |
| SCHEMBL3041381 | 0.85 | MAOA (0.40) | MAOAGRIN1GRIN2BMAOBCALML3 | |
| SCHEMBL3033115 | 0.76 | MAOA (0.53) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL3041348 | 0.74 | MAOA (0.51) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL5764939 | 0.74 | MAOA (0.51) | MAOAMAOBCALML3LMNAPTGS1 | |
| SCHEMBL4871651 | 0.74 | MAOA (0.47) | MAOAGRIN1GRIN2BMAOBCALML3 | |
| SCHEMBL4882399 | 0.74 | MAOA (0.43) | MAOAGRIN1GRIN2BMAOBCALML3 | |
| SCHEMBL3029181 | 0.73 | MAOA (0.46) | MAOACALML3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1478629-B1 | N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS | PHARMACIA & UPJOHN CO LLC (US) | 2006-10-11 | — | — | EP | disclosed |