Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 19/20 | 0.63 |
| ▸ | PLA2G1B | P04054 | 8/20 | 0.63 |
| ▸ | PLA2G10 | O15496 | 7/20 | 0.63 |
| ▸ | PLA2G2E | Q9NZK7 | 7/20 | 0.63 |
| ▸ | PLA2G5 | P39877 | 5/20 | 0.63 |
| ▸ | PLA2G2D | Q9UNK4 | 5/20 | 0.63 |
| ▸ | PLA2G2F | Q9BZM2 | 4/20 | 0.63 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.63 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.63 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.63 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.63 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5762011 | 0.92 | PLA2G2A (0.68) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL5762592 | 0.91 | PLA2G2A (0.57) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL5762824 | 0.90 | PLA2G2A (0.54) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL5762900 | 0.89 | PLA2G2A (0.66) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL5763265 | 0.88 | PLA2G2A (0.52) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL5763594 | 0.86 | PLA2G2A (0.61) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL5762562 | 0.85 | PLA2G2A (0.59) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL3198502 | 0.84 | PLA2G2A (0.72) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL5764980 | 0.84 | PLA2G2A (0.58) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 | |
| SCHEMBL5762119 | 0.83 | PLA2G2A (0.58) | PLA2G2APLA2G1BPLA2G10PLA2G2EPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091738-B1 | BICYCLIC sPLA 2 INHIBITORS | LILLY CO ELI (US) | 2006-12-06 | — | — | EP | disclosed |
| US-6384041-B1 | ANTIINFLAMMATORY AGENT, TREATMENT OF SHOCK AND ENZYME INHIBITORS | ELI LILLY AND COMPANY | 2002-05-07 | — | — | US | disclosed |