Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 20/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3842793 | 1.00 | P2RX7 (0.68) | P2RX7 | |
| SCHEMBL1802127 | 0.90 | P2RX7 (0.82) | P2RX7 | |
| Hydrochloric Acid SCHEMBL3839613 | 0.90 | P2RX7 (0.81) | P2RX7 | |
| SCHEMBL3837384 | 0.87 | P2RX7 (0.64) | P2RX7 | |
| SCHEMBL3837373 | 0.86 | P2RX7 (0.75) | P2RX7 | |
| SCHEMBL5767624 | 0.85 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL1805240 | 0.85 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL1805331 | 0.85 | P2RX7 (0.69) | P2RX7 | |
| SCHEMBL1806738 | 0.85 | P2RX7 (0.68) | P2RX7 | |
| Hydrochloric Acid SCHEMBL3837926 | 0.85 | P2RX7 (0.74) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1633717-A1 | NEW P2X7 RECEPTOR ANTAGONISTS AND THEIR USE | AstraZeneca AB (SE) | 2006-03-15 | — | — | EP | disclosed |
| WO-2004106305-A1 | NEW P2X7 RECEPTOR ANTAGONISTS AND THEIR USE | ASTRAZENECA AB (SE) | 2004-12-09 | — | — | WO | disclosed |