Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 6/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | QPCT | Q16769 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767404 | 0.90 | FGFR1 (0.42) | KDRFGFR1IRAK4PDGFRBPDGFRA | |
| SCHEMBL5767156 | 0.88 | KDR (0.46) | KDRFGFR1IRAK4ALDH1A1MAPT | |
| SCHEMBL5766162 | 0.88 | KDR (0.46) | KDRFGFR1IRAK4ALDH1A1MAPT | |
| SCHEMBL5766687 | 0.86 | KDR (0.44) | KDRFGFR1IRAK4ALDH1A1MAPT | |
| SCHEMBL5767252 | 0.84 | FGFR1 (0.46) | KDRFGFR1IRAK4ALDH1A1MAPT | |
| SCHEMBL5763180 | 0.84 | IRAK4 (0.48) | KDRFGFR1IRAK4ALDH1A1MAPT | |
| SCHEMBL5768204 | 0.82 | FGFR1 (0.56) | KDRFGFR1IRAK4ALDH1A1MAPT | |
| SCHEMBL5767694 | 0.79 | MAPT (0.42) | KDRFGFR1ALDH1A1MAPTHPGD | |
| SCHEMBL5766182 | 0.79 | FGFR1 (0.43) | KDRFGFR1IRAK4ALDH1A1MAPT | |
| SCHEMBL5767448 | 0.79 | FGFR1 (0.45) | KDRFGFR1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235825-B1 | NOVEL BENZOIMIDAZOLE DERIVATIVES USEFUL AS ANTIPROLIFERATIVE AGENTS | PFIZER PROD INC (US) | 2006-01-25 | — | — | EP | claimed |