SCHEMBL5767289

SCHEMBL5767289

NC(=O)C1CN(c2cc(F)c(C3=CCN(C(=O)[C@@H](O)CO)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.48

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.48
BTK Q06187 3/20 0.32
TRPV1 Q8NER1 6/20 0.31
CALML3 P27482 2/20 0.31
F10 P00742 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3042429 1.00 MAOA (0.48) MAOABTKTRPV1CALML3F10
SCHEMBL3039692 0.90 MAOA (0.46) MAOABTK
SCHEMBL3044448 0.90 MAOA (0.38) MAOABTKTRPV1CALML3F10
SCHEMBL3039686 0.90 MAOA (0.45) MAOABTKF10
SCHEMBL3045490 0.89 MAOA (0.46) MAOACALML3
SCHEMBL3033104 0.89 MAOA (0.46) MAOACALML3
SCHEMBL3039695 0.85 MAOA (0.46) MAOABTK
SCHEMBL6765855 0.81 TRPV1 (0.30) MAOABTKTRPV1
SCHEMBL3029331 0.81 MAOA (0.36) MAOABTKCALML3F10
SCHEMBL5233346 0.81 MAOA (0.35) MAOACALML3F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1478629-B1 N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS PHARMACIA & UPJOHN CO LLC (US) 2006-10-11 EP disclosed