⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6013891 | 0.89 | DNM1 (0.42) | — | |
| SCHEMBL22166182 | 0.81 | — | — | |
| SCHEMBL31499191 | 0.78 | — | — | |
| SCHEMBL25842982 | 0.74 | — | — | |
| SCHEMBL27863636 | 0.73 | — | — | |
| SCHEMBL10338222 | 0.73 | — | — | |
| SCHEMBL5077188 | 0.71 | — | — | |
| SCHEMBL5404936 | 0.71 | — | — | |
| SCHEMBL10754515 | 0.71 | — | — | |
| SCHEMBL5075973 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654257-A1 | AMINOPYRONES AND THEIR USE AS ATM INHIBITORS | Kudos Pharmaceuticals Limited (GB) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016919-A1 | AMINOPYRONES AND THEIR USE AS ATM INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2005-02-24 | — | — | WO | disclosed |
| EP-1485377-A1 | PYRANONES USEFUL AS ATM INHIBITORS | Kudos Pharmaceuticals Limited (GB) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003070726-A1 | PYRANONES USEFUL AS ATM INHIBITORS | KUDOS PHARMACEUTICALS LTD (GB) | 2003-08-28 | — | — | WO | disclosed |