Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBAL3 | A6NHL2 | 2/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.33 |
| ▸ | TUBA8 | Q9NY65 | 2/20 | 0.33 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | PDCD4 | Q53EL6 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10749094 | 0.74 | — | — | |
| SCHEMBL1107376 | 0.74 | — | — | |
| SCHEMBL10330199 | 0.74 | — | — | |
| SCHEMBL18196028 | 0.70 | PDCD4 (0.38) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL18196046 | 0.70 | PDCD4 (0.38) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL18196045 | 0.70 | PDCD4 (0.38) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL19297926 | 0.68 | IDUA (0.39) | PDCD4 | |
| SCHEMBL19297933 | 0.65 | PDCD4 (0.36) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL19297948 | 0.65 | PDCD4 (0.36) | TUBAL3TUBA3CTUBA1BTUBA4ATUBA3E | |
| SCHEMBL6633472 | 0.62 | XPO1 (0.40) | XPO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1667994-A1 | QUINOLONE ANTIBACTERIAL AGENTS | Warner-Lambert Company LLC (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20050119231-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-06-02 | — | — | US | disclosed |
| US-20050107423-A1 | Quinolone antibacterial agents | ELLSWORTH EDMUND L (US) | 2005-05-19 | — | — | US | disclosed |
| WO-2005026154-A1 | QUINOLONE ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY LLC (US) | 2005-03-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119231-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | TUBAL3 385/4885TUBA3C 182/4885TUBA1B 159/4885 |
| US-20050107423-A1 | Quinolone antibacterial agents | NQO2, MRPL21, TOP1 | TUBAL3 385/4885TUBA3C 182/4885TUBA1B 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.