Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD4 | Q53EL6 | 3/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.35 |
| ▸ | RELA | Q04206 | 2/20 | 0.35 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | TUBAL3 | A6NHL2 | 2/20 | 0.32 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.32 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.32 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.32 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.32 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.32 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.32 |
| ▸ | TUBA8 | Q9NY65 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19297933 | 1.00 | PDCD4 (0.36) | PDCD4NFKB1NFKB2RELAXPO1 | |
| SCHEMBL19284482 | 1.00 | PDCD4 (0.36) | PDCD4NFKB1NFKB2RELAXPO1 | |
| SCHEMBL20246837 | 0.81 | XPO1 (0.37) | PDCD4NFKB1NFKB2RELAXPO1 | |
| SCHEMBL18196045 | 0.74 | PDCD4 (0.38) | PDCD4XPO1TUBAL3TUBA3CTUBA1B | |
| SCHEMBL18196028 | 0.74 | PDCD4 (0.38) | PDCD4XPO1TUBAL3TUBA3CTUBA1B | |
| SCHEMBL8974583 | 0.71 | TSHR (0.39) | NFKB1NFKB2RELAGSK3AGSK3B | |
| SCHEMBL23638982 | 0.70 | NFKB1 (0.33) | NFKB1NFKB2RELAKDM4EKMT2A | |
| SCHEMBL23922439 | 0.69 | GSK3A (0.41) | NFKB1NFKB2RELAGSK3AGSK3B | |
| SCHEMBL10330199 | 0.67 | — | — | |
| SCHEMBL14966326 | 0.65 | POLB (0.51) | KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210214298-A1 | DEOXYDEHYDRATION OF SUGAR DERIVATIVES | UNIV CALIFORNIA (US) | 2021-07-15 | — | — | US | disclosed |
| WO-2017147098-A1 | DEOXYDEHYDRATION OF SUGAR DERIVATIVES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-08-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210214298-A1 | DEOXYDEHYDRATION OF SUGAR DERIVATIVES | GCK, G6PD, SLC2A4 | PDCD4 1259/4885NFKB1 3757/4885NFKB2 3159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.