Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 10/20 | 0.51 |
| ▸ | MAPK13 | O15264 | 7/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 7/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 7/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5770991 | 0.91 | MAPK14 (0.52) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5768951 | 0.89 | MAPK14 (0.59) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5769746 | 0.88 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11MAPK10 | |
| SCHEMBL5772227 | 0.88 | MAPK14 (0.57) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5772598 | 0.86 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5769553 | 0.86 | MAPK13 (0.56) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5771702 | 0.86 | MAPK13 (0.52) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5767950 | 0.86 | MAPK14 (0.51) | MAPK14MAPK13MAPK12MAPK11MAPK10 | |
| SCHEMBL5769992 | 0.85 | MAPK13 (0.64) | MAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL5770215 | 0.85 | MAPK14 (0.58) | MAPK14MAPK13MAPK12MAPK11MAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0988301-B1 | IMIDAZOLYL-CYCLIC ACETALS | AVENTIS PHARMA LTD (GB) | 2006-08-09 | — | — | EP | disclosed |
| US-6602877-B1 | Imidazolyl-cyclic acetals | AVENTIS PHARMA LIMITED (GB) | 2003-08-05 | — | — | US | disclosed |