SCHEMBL5767950 — predicted protein targets

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	MAPK14	Q16539	11/20	0.51

▸	MAPK13	O15264	8/20	0.51

▸	MAPK12	P53778	8/20	0.51

▸	MAPK11	Q15759	8/20	0.51

▸	MAPK10	P53779	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL5770994	0.92	MAPK14 (0.52)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5768953	0.90	MAPK13 (0.59)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5769751	0.89	MAPK14 (0.51)	MAPK14MAPK13MAPK12MAPK11MAPK10
SCHEMBL5771702	0.89	MAPK13 (0.52)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5772234	0.88	MAPK13 (0.57)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5772601	0.87	MAPK13 (0.58)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5770908	0.87	MAPK13 (0.56)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5769998	0.86	MAPK13 (0.64)	MAPK14MAPK13MAPK12MAPK11
SCHEMBL5767948	0.86	MAPK14 (0.51)	MAPK14MAPK13MAPK12MAPK11MAPK10
SCHEMBL5770215	0.86	MAPK14 (0.58)	MAPK14MAPK13MAPK12MAPK11MAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0988301-B1	IMIDAZOLYL-CYCLIC ACETALS	AVENTIS PHARMA LTD (GB)	2006-08-09	—	—	EP	disclosed
US-6602877-B1	Imidazolyl-cyclic acetals	AVENTIS PHARMA LIMITED (GB)	2003-08-05	—	—	US	disclosed