SCHEMBL5768

SCHEMBL5768

Cc1cccc(N)c1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2015386 0.80
SCHEMBL8164803 0.80 ALDH1A1 (0.53)
SCHEMBL62013 0.80
SCHEMBL126987 0.77 ALDH1A1 (0.50)
SCHEMBL10798531 0.76 CYP3A4 (0.46)
SCHEMBL30839716 0.75 CD44 (0.65)
SCHEMBL3462069 0.75 CD44 (0.65)
SCHEMBL686929 0.75
SCHEMBL29661770 0.75
SCHEMBL16497559 0.72 CD44 (0.62)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 415 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
CN-118373783-A Method for preparing topramezone intermediate dihydro-isoxazole compound 帕潘纳(北京)科技有限公司 2024-07-23 CN claimed
CN-113214041-A Novel method for preparing 3-iodine-2 bromotoluene 河北唯达生物医药产业技术研究有限公司 2021-08-06 CN claimed
CN-112876411-A Compound and application thereof in synthesis of PDL1 antagonist drug molecules 杭州阿诺生物医药科技有限公司 2021-06-01 CN claimed
CN-103041855-B Preparation method of catalysts for dichloro-pyridine oxynitride SHANGHAI NOVEL CHEMICAL TECHNOLOGY CO LTD 2014-09-10 CN claimed
US-12630566-B2 KRas G12D inhibitors Mirati Therapeutics, Inc. (US) 2026-05-19 US disclosed
EP-4695235-A1 NOVEL GSPT1 DEGRADER AND USE THEREOF Cyrus Therapeutics Inc. (KR) 2026-02-18 EP disclosed
US-20260042791-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2026-02-12 US disclosed
EP-3915996-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2025-09-10 EP disclosed
EP-4580621-A2 T-TYPE VOLTAGE-GATED CALCIUM CHANNEL POTENTIATORS The Broad Institute, Inc. (US) 2025-07-09 EP disclosed
US-12344586-B2 Process for the preparation of biphenylamines ADAMA MAKHTESHIM LTD. (IL) 2025-07-01 US disclosed
CN-120091815-A T-type voltage-gated calcium channel enhancer 广泛研究所股份有限公司 2025-06-03 CN disclosed
US-5635528-A RECEPTOR BINDING MODULATORS, FOR CENTRAL NERVOUS SYSTEM DISORDERS ELI LILLY AND COMPANY (US) 1997-06-03 US disclosed
CN-1148340-A Treatment of 5HTZBMethods of receptor-related disorders LILLY CO ELI (US) 1997-04-23 CN disclosed
EP-0749313-A1 METHOD FOR TREATING 5HT 2B RECEPTOR RELATED CONDITIONS ELI LILLY AND COMPANY (US) 1996-12-27 EP disclosed
US-5508284-A TREATING 5-HYDROXYTRYPTAMINE MODULATION ELI LILLY AND COMPANY (US) 1996-04-16 US disclosed
US-5500431-A ANTISEROTONINE AGENTS; SEXUAL AND EATING DISORDERS ELI LILLY AND COMPANY (US) 1996-03-19 US disclosed
WO-1995024200-A1 METHOD FOR TREATING 5HT2B RECEPTOR RELATED CONDITIONS ELI LILLY AND COMPANY (US) 1995-09-14 WO disclosed
WO-1994023720-A1 TETRAHYDRO-BETA-CARBOLINES ELI LILLY AND COMPANY (US) 1994-10-27 WO disclosed
EP-0620222-A2 Tetrahydro-beta-carbolines ELI LILLY AND COMPANY (US) 1994-10-19 EP disclosed