Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.72 |
| ▸ | PTPRF | P10586 | 1/20 | 0.56 |
| ▸ | PTPRA | P18433 | 1/20 | 0.56 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5743653 | 0.90 | PTPN1 (0.83) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7497194 | 0.84 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL3867351 | 0.83 | PTPN1 (0.77) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL13888092 | 0.83 | PTPN1 (0.72) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL3868415 | 0.82 | PTPN1 (0.97) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL3871852 | 0.82 | PTPN1 (0.71) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4478559 | 0.81 | PTPN1 (0.79) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7597537 | 0.78 | PTPN1 (0.72) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7504747 | 0.78 | PTPN1 (0.72) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4459365 | 0.78 | PTPN1 (0.68) | PTPN1PTPRFPTPRAPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2006525329-A | — | — | 2006-11-09 | — | — | JP | claimed |
| EP-1620420-A2 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | claimed |
| WO-2004099168-A2 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | claimed |
| EP-1620420-A2 | SUBSTITUTED CARBOXYLIC ACIDS | The Institutes for Pharmaceutical Discovery, LLC (US) | 2006-02-01 | — | — | EP | disclosed |
| WO-2004099168-A2 | SUBSTITUTED CARBOXYLIC ACIDS | THE INSTITUTES FOR PHARMACEUTICAL DISCOVERY, LLC (US) | 2004-11-18 | — | — | WO | disclosed |