Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 20/20 | 0.72 |
| ▸ | PTPRF | P10586 | 1/20 | 0.54 |
| ▸ | PTPRA | P18433 | 1/20 | 0.54 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7504747 | 0.85 | PTPN1 (0.72) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7497194 | 0.84 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL5743653 | 0.84 | PTPN1 (0.83) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL3868415 | 0.83 | PTPN1 (0.97) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL3867351 | 0.80 | PTPN1 (0.77) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7505847 | 0.79 | PTPN1 (0.70) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL7510322 | 0.79 | PTPN1 (1.00) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4271340 | 0.78 | PTPN1 (0.67) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL4478559 | 0.78 | PTPN1 (0.79) | PTPN1PTPRFPTPRAPTPN7DUSP3 | |
| SCHEMBL5768084 | 0.78 | PTPN1 (0.72) | PTPN1PTPRFPTPRAPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077966-B1 | BIPHENYL SULFONYL ARYL CARBOXYLIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | WYETH CORP (US) | 2002-11-20 | — | — | EP | disclosed |
| US-6310081-B1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION | 2001-10-30 | — | — | US | disclosed |
| US-6221902-B1 | HYPOGLYCEMIC AGENTS; ANTIDIABETIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION | 2001-04-24 | — | — | US | disclosed |
| EP-1077966-A1 | BIPHENYL SULFONYL ARYL CARBOXYLIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058520-A1 | BIPHENYL SULFONYL ARYL CARBOXYLIC ACIDS USEFUL IN THE TREATMENT OF INSULIN RESISTANCE AND HYPERGLYCEMIA | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-11-18 | — | — | WO | disclosed |