Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 13/20 | 0.56 |
| ▸ | HTR2A | P28223 | 12/20 | 0.56 |
| ▸ | DRD2 | P14416 | 10/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5767115 | 0.89 | HTR2A (0.57) | HTR1AKCNH2HTR2ADRD2HTR7 | |
| SCHEMBL5768141 | 0.89 | HTR1A (0.56) | HTR1AKCNH2HTR2ADRD2HTR7 | |
| SCHEMBL5763496 | 0.79 | HTR2A (0.51) | HTR1AKCNH2HTR2ADRD2HTR7 | |
| SCHEMBL6106723 | 0.78 | HTR1A (0.56) | HTR1AKCNH2HTR2ADRD2HTR7 | |
| SCHEMBL6105381 | 0.78 | HTR1A (0.60) | HTR1AKCNH2HTR2ADRD2HTR7 | |
| SCHEMBL5794638 | 0.77 | HTR2A (0.51) | HTR1AKCNH2HTR2ADRD2HTR7 | |
| SCHEMBL6218582 | 0.76 | HTR1A (0.60) | HTR1AKCNH2HTR2ADRD2HTR7 | |
| SCHEMBL5738492 | 0.76 | HTR1A (0.64) | HTR1AKCNH2HTR2ADRD2HTR7 | |
| SCHEMBL5764322 | 0.76 | HTR2A (0.58) | HTR1AKCNH2HTR2ADRD2HTR7 | |
| SCHEMBL6795579 | 0.76 | HTR1A (0.59) | HTR1AKCNH2HTR2ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701954-A1 | N-SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES | Warner-Lambert Company LLC (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005066165-A1 | N-SUBSTITUTED PIPERIDINE AND PIPERAZINE DERIVATIVES | WARNER-LAMBERT COMPANY LLC (US) | 2005-07-21 | — | — | WO | disclosed |