Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.41 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL386879 | 0.79 | GAA (0.52) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL386878 | 0.79 | GAA (0.52) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL11371297 | 0.71 | JAK3 (0.35) | ALDH1A1POLB | |
| SCHEMBL9345444 | 0.67 | RAB9A (0.53) | KDM4EALDH1A1HPGDCYP1A2CYP2C9 | |
| SCHEMBL9349268 | 0.67 | RAB9A (0.53) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9349509 | 0.66 | RAB9A (0.52) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9344238 | 0.66 | RAB9A (0.52) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9346149 | 0.65 | RAB9A (0.51) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9346379 | 0.65 | RAB9A (0.51) | KDM4EALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9345157 | 0.65 | RAB9A (0.45) | KDM4EALDH1A1HPGDHSD17B10POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711491-A1 | HETEROCYCLIC DERIVATIVES AS GPCR RECEPTOR AGONISTS | Prosidion Limited (GB) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005061489-A1 | HETEROCYCLIC DERIVATIVES AS GPCR RECEPTOR AGONISTS | PROSIDION LIMITED (GB) | 2005-07-07 | — | — | WO | disclosed |